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Hyaluronidase
Product Name :  Hyaluronidase
CAS No. : 9001-54-1
Source: mammalian testes
EC: 3.2.1.35
DESCRIPTION
Hyaluronidase appearance is white or yellowish-white, amorphous powder, soluble in water, practically insoluble in acetone and in ethanol.
Hyaluronidase is a glycoprotein containing 5% mannose and 2.7% glucosamine. Optimum pH range is 4.5-6.0. The enzyme catalyzes the hydrolysis of endo-N-acetylhexosaminic bonds of hyaluronic acid and chondroitin sulfate A and C (but not B), primarily to tetrasaccharide residues.
Hyaluronidase is extracted from bovine testes or ovine testes, and has been chromatographically purified to remove trace contaminating proteases.
SPECIFICATION:

Item

Specification

Method

[Appearance]

A white or yellowis-white powder

 

[Identification]

Complies

EP

pH

4.5 – 7.5

EP

Appearance of solution

Clear

EP

Loss on drying

≤ 5.0%

EP

Bacterial endotoxins

Less than 0.2 IU per IU of hyaluronidase

EP

Limit of tyrosine

≤ 0.25 μg per USP Hyaluronidase U.

USP

Activity

≥ 300 IU/mg powder

EP


Activity:300IU/mg -2000 IU/mg
Standard: CP / USP / EP
STORAGE
Store in an airtight container, at a temperature of 2°C to 8°C, or below.
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