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| Products |
| Ribonuclease A
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Source: Bovine Pancrease
EC:3.1.27.5
DESCRIPTION
Pancreatic Ribonuclease (RNase I) catalyzes cleavage of the phosphodiester bond between the 5'-ribose of a nucleotide and the phosphate group attached to the 3'-ribose of an adjacent pyrimidine nucleotide forming a 2',3'-cyclic phosphate which may then be hydrolyzed to the corresponding 3'-nucleoside phosphate. Ribonuclease A has a molecular weight of 13,700 daltons. It operates in an optimum pH range of 7.0-7.5.
Ribonuclease has been further purified by affinity chromatography method to remove trace contaminating proteases.
SPECIFICATION
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Item
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Specification
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Method
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Appearance
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White to pale yellow lyophilized powder
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Appearance of solution
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Not more opalescent than ref. suspension II
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USP
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Loss on drying
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≤ 5.0%
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USP
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DNase contamination
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Not detectable
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Sigma
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Activity
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≥ 50 Kunitz units/mg
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Sigma
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STORAGE
Store in an airtight container, at a temperature of 2°C to 8°C.
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| Previous:Deoxyribonuclease I |
| Next:Trypsin 1:250 |
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