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| Products |
| Pharmaceutical Grade Sodium Hyaluronate
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Sodium Hyaluronate is an important component of intercellular substance, eye vitreous body, joint fluid and other connective tissue. It acts the important physiologic roles in holding body's moisture, maintaining extracellular space, adjusting osmotic pressure, lubricating and promoting cells to repair in the body. Sodium Hyaluronate can be used as viscoelastic agent inintraocular lens implantation operation, as the filler in the osteoarthritis and rheumatoid arthritis and otherjoint surgery, as a medium widely used in eye drops, it also can be used to prevent postoperative adhesion and facilitate the wound heal. The compounds formed by the reaction of Sodium Hyaluronate with other drugs play a drug release effect role, thus achieve the purpose of drug targeted and time controlled release.
With the development of medical technology, Sodium Hyaluronate has been more and more widely used in medical applications.In 1976, Sodium Hyaluronate was first commercialized and used as ophthalmic viscoelastic agents, which is a significant progress in the ophthalmic industry. In 1987, Sodium Hyaluronate for intra-articular injection came in to the market. In 1990s, the large-scale production of Sodium Hyaluronate by fermentation made the cost lower, thus products containing Sodium Hyaluronate such as eye-drops, dermal fillers and other Sodium Hyaluronate preparations started to be used extensively.
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Item
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Standard
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Appearance
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White powder
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Solubility
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Soluble in water, practically insoluble in acetone and in anhydrous ethanol.
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Glucuronic Acid
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Min.46%
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Sodium Hyaluronate
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Min.95%
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Appearance of Solution
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A600nm≤ 0.01
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Nucleic Acid
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A260nm≤ 0.5
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pH
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6.0-7.5
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Molecular Weight
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2.0-3.0 Million Daltons
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Protein
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Max.0.05%
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Loss on drying
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Max.10%
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Residue on Ignition
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Max.20%
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Chlorides
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Max.0.5%
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Iron
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Max.80ppm
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Heavy metal
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Max.20ppm
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Arsenic
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Max.2ppm
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Nitrogen
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3.0-4.0%
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Bacteria Count
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Max.10CFU/g
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Molds & Yeast
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Max.10CFU/g
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Staphylococcus aureus
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Negative
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Pseudomonas aeruginosa
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Negative
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Hemolysis
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Negative
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Viable Hemolytical Streptococci
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Negative
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Endotoxin Level
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Max.0.5 IU/ mg or Max.0.05IU/ mg
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Standard: BP/EP/USP.
Molecular Weight (Dalton):
1. Medium MW: >2.0 * 106 Dalton
2. High MW: > 3.0 * 106 Dalton
Usage Scope: Cataract Surgery. Glaucoma Surgery. Corneal transplant surgery. Retinal attachment surgery. Skin filler. Anti-wrinkle. Arthritis-Injection
Package: 100g/sterile bottle. 1kg/box.
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| Next:Cosmetic Grade Sodium Hyaluronate |
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